It's no secret that the health of the surrounding tissue plays a great role in the success of a dental implant, and that is why identifying and reducing risk factors is the most important step in the implant process. A recent study showed that "a combination of genes has been identified as a possible indicator of greater tissue destruction leading to negative outcomes for implants."
The process of tissue inflammation and destruction is very similar to periodontal disease. The researchers were trying to find any association of these genotypes.
All of the patients in the study had implants. People were divided in two groups, which then were compared, "The first group consisted of 25 patients with peri-implantitis, at the same time, the second group of 25 patients had healthy tissue. Seventeen patients from the first group and five from the second group were genotype positive."
The study concluded that, "The combination of these two alleles in patients with inflamed periodontal tissues denotes a risk factor that can lead to further tissue destruction. Patients with the specific genotype can have exaggerated local inflammation. Gene polymorphism may affect the outcomes of treatment for peri-implantitis in genotype-positive people and affect the long-term success of implants."
Source: Allen Press Publishing Services
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